Maternal Exposure to Trichloroethylene in Drinking Water and Birth-Weight Outcomes |
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| Authors: | Sven E. Rodenbeck Lee M. Sanderson Antonio Rene |
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| Affiliation: | 1. Division of Health Assessment and Consultation Agency for Toxic Substances and Disease Registry Public Health Service, U.S. Department of Health and Human Services;2. Division of Health Assessment and Consultation , Agency for Toxic Substances and Disease Registry Public Health Service, U.S. Department of Health and Human Services;3. School of Public Health University of North Texas Health Science Center at Fort Worth , Fort Worth, Texas |
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| Abstract: | An ecological epidemiological study was conducted with data obtained from an environmental dose-reconstruction study and the Arizona Birth Information Tapes. Before 1981, a portion of the city of Tucson water-distribution system was contaminated with trichloroethylene (i.e., < 5 micrograms per liter of water to 107 micrograms per liter of water). Target and comparison populations were selected with a Geographic Information System. Logistical-regression analysis revealed an association between maternal exposure to trichloroethylene via drinking water and very-low-birth-weight babies (i.e., < 1,501 grams) (odds ratio = 3.3; 95% confidence interval = 0.5, 20.6; and Wald chi-square p value = 0.2). No association was found between maternal exposure to trichloroethylene via drinking water and low birth weight or full-term low-birth-weight infants (gestational period > 35 wk and < 46 wk). |
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| Keywords: | allergy diesel-exhaust particles IgE immunoglobulin E road traffic pollution |
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