| 急性哮喘患者血浆中C3a含量变化的临床意义 |
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| 引用本文： | 陶玉滨,杜民,许勇臣. 急性哮喘患者血浆中C3a含量变化的临床意义[J]. 解放军保健医学杂志, 2005, 7(4): 221-222 |
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| 作者姓名： | 陶玉滨 杜民 许勇臣 |
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| 作者单位： | 解放军211医院 黑龙江哈尔滨150080 |
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| 摘 要： | 目的探讨支气管哮喘患者血浆中补体3a(C3a)含量变化,旨在说明C3a与哮喘表现间的关系。方法采集56例支气管哮喘患者急性发作期、缓解期及30例健康人外周血,放射免疫法检测血浆C3a/去精氨酸C3a的含量。结果支气管哮喘患者急性发作期血浆C3a含量为230±150ng/ml,缓解期为170±132ng/ml,健康对照组为164±140ng/ml,急性发作期血浆C3a含量明显高于缓解期和对照组(P<0.05),而缓解期与对照组间无显著差异(P>0.05)。结论C3a可能参与支气管哮喘急性发作时的病理生理过程。
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| 关 键 词： | 哮喘 补体3a |
| 文章编号： | 1673-1913（2005）04-0221-02 |
| 收稿时间： | 2005-03-16 |
| 修稿时间： | 2005-03-16 |
Implications of plasma C3a level in acute asthmatic patients |
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| TAO Yubin,DU Min,XU Yongchen=. Implications of plasma C3a level in acute asthmatic patients[J]. Journal Of Health Care And Medicine in Chinese Pla, 2005, 7(4): 221-222 |
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| Authors: | TAO Yubin DU Min XU Yongchen= |
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| Abstract: | Objective To evaluate the relationship between plasma C3a level and asthma and show the role of C3a in asthma pathogenetics.Methods The plasma C3a/C3a des-arginine concentrations of 56 acute and stable state asthmatics as well as the control were detected with radioimmunoassay.Results The concentration of plasma C3a/C3a des-arginine of acute asthma was highest among three group(P<0.05) and there was no significiant difference between that of the stable ones and the control(P>0.05).Conclusions C3a,as an anaphylatoxin was involved in the pathophysiological process of acute asthma. |
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| Keywords: | asthma complement 3a |
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