脑卒中后抑郁症72例临床分析

目的: 探讨脑卒中后抑郁症(poststroke depression,PSD)发生特点、相关因素及其预后。方法: 采用抑郁自评量表(SDS)和汉密尔顿抑郁量表(HAMD),调查192例脑卒中患者抑郁发生情况及临床特点。结果: PSD总发生率37.5%(其中轻度抑郁发生率20.8%,中度10.4%,重度6.3%),PSD发病与脑卒中发病部位、神经功能缺损严重程度有密切的关系。结论: 脑卒中后抑郁是脑卒中的常见并发症,与神经功能缺损日常生活能力依赖有密切关系,早期加抗抑郁剂治疗能提高患者的生活质量和神经功能的康复。

Clinical analysis of poststroke depression:Report of 72 cases

Objective: To explore the characteristics,related factors and prognosis of poststroke depression(PSD).Methods: One hundred and ninety-two patients with cerebral stroke were investigated by sefl-rating depression scale(SDS) and Hamilton rating scall for depression(HAMD) about the occurrence of PSD and the clinical characteristics.Results: The occurrence rate of PSD was 37.5%.Among them,light deppression accounted for 20.8%,medium deppression 10.4% and heavy deppression 6.3%.The PSD was closely related to the damage situs and the degree of cerebral stroke.Conclusions: PSD is a familiar complication after cerebral stroke.It is closely related to the damage of nerve function and the patients' ability of daily living.Application of antidepressant agents in early treatment can improve the patients' life quality and recovery of nerve function.