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Laryngopharyngeal reflux in patients with reflux esophagitis
Authors:Lai Yung-Chih  Wang Pa-Chun  Lin Jun-Chen
Affiliation:1. Division of Gastroenterology, Department of Internal Medicine, Cathay General Hospital, School of Medicine, National Taiwan University, School of Medicine, Taipei Medical University, Taipei 10630, Taiwan, China
2. Department of Otolaryngology, Cathay General Hospital; School of Medicine, Fu Jen Catholic University, Taipei 10630; School of Public Health, China Medical University, Taichung 40402, Taiwan, China
3. Department of Otolaryngology, Cathay General Hospital, Taipei 10630, Taiwan, China
Abstract:AIM: To assess the prevalence of laryngopharyngeal reflux (LPR) in patients with reflux esophagitis and dis-close factors contributing to the development of LPR.METHODS: A total of 167 patients who proved to have reflux esophagitis by endoscopy were enrolled.ings for the diagnosis of LPR. We used validated ques-tionnaires to identify the presence of laryngopharyn-geal symptoms, and stringent criteria of inclusion to increase the specificity of laryngoscopic findings. The data of patients were analyzed statistically to find out factors related to LPR.RESULTS: The prevalence rate of LPR in studied sub-jects with reflux esophagitis was 23.9%. Age, hoarse-ness and hiatus hernia were factors significantly as-sociated with LPR. In 23 patients with a hiatus hernia,the group with LPR was found to have a lower trend of esophagitis grading.CONCLUSION: Laryngopharyngeal reflux is present in patients with reflux esophagitis, and three predicting factors were identified. However, the development of LPR might be different from that of reflux esophagi-tis. The importance of hiatus hernia deserves further study.
Keywords:Laryngopharyngeal reflux  Gastroesopha-geal reflux disease  Reflux esophagitis
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