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反复针刺分离联合结膜下注射5-FU治疗青光眼术后滤过泡功能不良
引用本文:刘毅,蔡岩,王新慧.反复针刺分离联合结膜下注射5-FU治疗青光眼术后滤过泡功能不良[J].国际眼科杂志,2013,13(7):1388-1390.
作者姓名:刘毅  蔡岩  王新慧
作者单位:中国新疆维吾尔自治区乌鲁木齐市,解放军第474医院眼科医院;中国新疆维吾尔自治区乌鲁木齐市,解放军第474医院眼科医院;中国新疆维吾尔自治区乌鲁木齐市,兰州军区乌鲁木齐总医院医务部
摘    要:目的:评估以反复针刺分离联合结膜下注射5-FU的方法处理青光眼术后功能不良滤过泡的效果。方法:回顾性分析2009-03/2013-02在我院以反复针刺分离联合结膜下注射5-FU的方法处理因青光眼术后滤过泡功能不良而眼压升高的连续病例34例34眼。分析治疗后眼压、滤过泡形态的变化及眼部并发症。结果:治疗后平均眼压从35.51mmHg降至14.43mmHg(P<0.05),成功率达91%。常见并发症包括角膜上皮损伤、结膜撕裂和脉络膜脱离等。结论:反复针刺分离联合结膜下注射5-FU的方法处理青光眼术后滤过泡功能不良安全有效。

关 键 词:滤过泡  青光眼  功能不良  5-FU  针刺分离  房角镜检查
收稿时间:2013/3/14 0:00:00
修稿时间:2013/6/26 0:00:00

Treating malfunction filtering bleb with repeated needling combined with adjunctive 5-FU after glaucoma filtration surgery
Yi Liu,Yan Cai and Xin-Hui Wang.Treating malfunction filtering bleb with repeated needling combined with adjunctive 5-FU after glaucoma filtration surgery[J].International Journal of Ophthalmology,2013,13(7):1388-1390.
Authors:Yi Liu  Yan Cai and Xin-Hui Wang
Institution:Department of Ophthalmology, No.474 Hospital of Chinese PLA, Urumchi 830000, Xinjiang Uygur Autonomous Region, China;Department of Ophthalmology, No.474 Hospital of Chinese PLA, Urumchi 830000, Xinjiang Uygur Autonomous Region, China;the Medical Department of Urumqi General Hospital of Lanzhou Military Area Command, Urumchi 830000, Xinjiang Uygur Autonomous Region, China
Abstract:AIM: To evaluate the therapeutic efficacy of a repeated bleb needling technique combined with subconjunctival injection of 5-FU in eyes with previous glaucoma surgery that had malfunctional filtering blebs.

METHODS: A retrospective review of 34 consecutive patients(34 eyes)of repeated bleb needling combined with subconjunctival injection of 5-FU in eyes, which had malfunctional filtering blebs after previous glaucoma surgery in our hospital from March 2009 to February 2013 was performed. The intraocular pressures(IOP), shapes of filtering blebs and complications after surgery were analyzed.

RESULTS: There was significant reduction of mean IOP from 35.51mmHg to 14.43mmHg(P<0.05). The overall success rate was 91%. The general complications included damage of corneal epithelium, conjunctiva torn, and choroidal detachment.

CONCLUSION: Repeated needling with adjunctive 5-FU proved a highly effective, safe alternative to treat malfunctional filtering blebs after previous glaucoma surgery.

Keywords:filtering bleb  glaucoma  malfunction  5-FU  needling  gonioscopy
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