自体肺体外循环实验动物模型的建立

目的：试建立自体肺体外循环实验动物模型。方法：杂种犬16只，静脉麻醉后气管插管行人工呼吸。开胸，右心房、肺动脉插管，连接贮血器、泵建立右心体外循环系统；左心房、升主动脉插管，连接贮血器、变温器和泵建立左心体外循环系统。结果：15只犬顺利建立自体肺体外循环，1只失败。结论：模型建立成功的要点是熟练的插管技术，左右心系统转流平衡，适宜的体温。

Establishment of an experimental model of autogenous oxygenator cardiopulmonary bypass in dogs

Objective:To establish an experimental autogenous oxygenator cardiopulmonary bypass in dogs.Methods:Sixteen mongrel dogs were used.Under intravenous anesthesia and artificial respiration,thoracotomy and cardiac cannulations were performed:right atrium cannulation and pulmonary artery cannulation,connecting to reservoir and pump,the right heart bypass system was established;left atrium and ascending aotra cannulation,connecting to reservoir,heat exchanger and pump,the left heart bypass was established.Results:The experimental model was established successfully in fifteen dogs and one failed.Conclusion:The susscessful establishment of this experimental model depends on skillful cannulation,balance of left and right circulation,appropriate body temperature.