Micropapillary variant of transitional cell carcinoma of the bladder |
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Authors: | YOSHIO SUGINO HIROMITSU NEGORO HIROSHI IWAMURA SEIJI MOROI HIROYA OKA MUTSUSHI KAWAKITA KEISUKE HANIOKA HIDEO TAKEUCHI |
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Affiliation: | Department of Urology, Kobe City General Hospital, Japan. sugifly@oak.ocn.ne.jp |
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Abstract: | A 77-year-old man visited the Kobe City General Hospital complaining of macroscopic hematuria. A computed tomography scan found a bladder tumor with left iliac and para-aortic lymph node metastasis. Two courses of cisplatin, cyclophosphamide and doxorubicin chemotherapy resulted in a minimal response. Radical cystectomy and a retroperitoneal lymph node dissection with bilateral ureterocutaneostomy reconstruction were then performed. A pathological examination revealed a micropapillary variant of transitional cell carcinoma (Grade 3, pT1pN2M1). The patient died of pelvic recurrence 7 months after the initiation of chemotherapy. Peritonitis carcinomatosa and lung metastases were observed at autopsy. |
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Keywords: | chemotherapy bladder tumor lymph node metastasis micropapillary variant transitional cell carcinoma |
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