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ECA透皮剂涂肤防护血吸虫感染的研究
引用本文:卢岳华,黄琼瑶,彭飞,刘年猛,孙慧,冯芳,胡琦,刘铭. ECA透皮剂涂肤防护血吸虫感染的研究[J]. 实用预防医学, 2003, 10(5): 712-713
作者姓名:卢岳华  黄琼瑶  彭飞  刘年猛  孙慧  冯芳  胡琦  刘铭
作者单位:湖南师范大学医学院,中国湖南,长沙,410006
基金项目:湖南省血吸虫病专家咨询委员会资助项目 (2 0 0 1 0 2 )
摘    要:目的 探讨 ECA透皮剂防护血吸虫感染的效果。 方法 以 10 % DMSO作溶剂配置不同浓度的 ECA透皮剂 ,涂于小鼠腹部 ,待干、泥浆摩擦后感染血吸虫尾蚴 ,观察防护作用。 结果  3% ECA透皮剂涂肤 ,10 0 %抵抗血吸虫感染 ;1%、0 .5 % ECA透皮剂防护率分别达 96 .91%、93.6 2 %。药物对皮肤无明显刺激。 结论 ECA透皮剂涂肤有防护日本血吸虫感染的作用

关 键 词:ECA透皮剂 血吸虫 防护率 防护剂 尾蚴
文章编号:1006-3110(2003)05-0712-02
修稿时间:2003-09-10

The Prevention from Schistosoma japonicum Cercariae Infection by Smearing Penetrating Agent of ECA
LU Yuehua,HUANG Qingyao,PENG Fei,et al.. The Prevention from Schistosoma japonicum Cercariae Infection by Smearing Penetrating Agent of ECA[J]. Practical Preventive Medicine, 2003, 10(5): 712-713
Authors:LU Yuehua  HUANG Qingyao  PENG Fei  et al.
Abstract:Objective The effect of prevention Schistosomn japonicum cercariae infection by smearing penetrating agent of ECA was observed. Methods The penetrating of ECA was compounded into different solution with 10% DMSO regarded as promoter and then were painted on the skin of mice for preventing infection of schistosoma japonicum cercariae. Result The preventing rates of mice smeared 3%,1% and 0.5% penetrating agent of ECA were 100%?96 91% and 93.62%. The drug has no action to skin of mice. Conclusion The penetrating agent of ECA smeared on skin of mice can prevent infection of schistosoma japonicum cercariae.
Keywords:Penetrating agent of ECA  Prevention  Schistosoma japonicum cercariae
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