| 白芍总苷对未分化结缔组织病高球蛋白血症影响的临床研究 |
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| 引用本文： | 沈友轩,刘晓华.白芍总苷对未分化结缔组织病高球蛋白血症影响的临床研究[J].中华风湿病学杂志,2005,9(1):39-41. |
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| 作者姓名： | 沈友轩 刘晓华 |
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| 作者单位： | 210029,南京医科大学第一附属医院风湿免疫科 |
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| 摘 要： | 目的观察白芍总苷对未分化结缔组织病高球蛋白血症的影响。方法选择50例未分化结缔组织病患者,随机分为治疗组(白芍总苷加胸腺肽、羟氯喹)和对照组(胸腺肽、羟氯喹),观察治疗3个月后免疫球蛋白变化。结果两组均可以使IgG、IgA下降,与对照组比较治疗组IgG在治疗后3个月,IgA在治疗后2个月下降幅度更为明显(P<0.05);治疗后3个月治疗组并能降低类风湿因子滴度。结论白芍总苷能改善未分化结缔组织病高球蛋白血症。
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| 关 键 词： | 结缔组织疾病 高球蛋白血症 白芍总苷 免疫球蛋白 治疗 |
| 修稿时间： | 2004年6月30日 |
Study of effect of total peony glucosides on hypergammaglobulinemia in undifferentiated connective tissue disease |
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| SHEN You-xuan,LIU Xiao-hua.Study of effect of total peony glucosides on hypergammaglobulinemia in undifferentiated connective tissue disease[J].Chinese Journal of Rheumatology,2005,9(1):39-41. |
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| Authors: | SHEN You-xuan LIU Xiao-hua |
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| Institution: | SHEN You-xuan,LIU Xiao-hua. Department of Rheumatology,The first Affiliated Hospital of Nanjing Medical University,Jiangsu 210029,China |
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| Abstract: | Objective To observe the effect of total glucosides of peony on hypergammaglobulinemia of undifferentiated connective tissue disease(UCTD). Methods Fifty patients with UCTD were randomly divided into the treat-ment group (total glucosides of peony and hydroxychloroquine and thymosin) (n=30) and the control group (hydroxychloroquine and thymosin) (n=20). The changes between the two groups on hypergammaglobulinemia after treated for 3 months were compared. Results The two groups all had the IgG and IgA decreased, but the treatment group decreased more significantly. In addition, the treatment group had decreased RF. Conclusion Total glucosides of peony can improve the hypergammaglobulinemia of UCTD. |
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| Keywords: | Connective tissue diseases Hypergammaglobulinemia Total glucosides of peony |
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