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Current Therapeutic Apheresis Technologies for Inflammatory Bowel Disease
Authors:Ken Yatnaji  Ken Fukunaga  Shingo Yamane  Akinori Sueoka  Yukihiko Nose
Abstract:Abstract: A large number of physicians have indicated that patients with inflammatory bowel diseases (IBD) such as ulcerative colitis (UC) and Crohn's disease (CD) respond to current apheresis technology treatment. However, the mechanism of the apheresis procedure is undefined for patients with IBD. IBD appears to be caused by a complex of interactions from the genes, environment, and the immune system; therefore, the immune system plays a crucial role in the inflammatory responses. In this process, lots of interactions occur simultaneously, and they cross relate with each other. This review paper briefly discusses the etiology and pathogenesis of IBD and attempts to elucidate the mechanism that occurs after apheresis treatment.
Keywords:Inflammatory bowel disease  Ulcerative colitis  Crohn's disease  Apheresis  Leukocytapheresis
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