| 三种常用中药注射液的过敏性研究 |
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| 引用本文： | 王增仙,武敏霞,高萧枫,李艳丽,王明军,李平.三种常用中药注射液的过敏性研究[J].山西中医学院学报,2011,12(4):5-7. |
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| 作者姓名： | 王增仙 武敏霞 高萧枫 李艳丽 王明军 李平 |
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| 作者单位： | 山西生物应用职业技术学院,山西,太原,030031 |
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| 摘 要： | 目的:探讨双黄连注射液、清开灵注射液和复方丹参注射液在皮肤被动过敏试验(PCA)和全身主动过敏试验(ASA)中是否有过敏反应。方法:按照《中药、天然药物免疫毒性(过敏性、光变态反应)研究的技术指导原则》的试验方法对以上3种注射液进行皮肤被动过敏试验和全身主动过敏试验研究。结果:皮肤被动过敏试验双黄连注射液有过敏反应;清开灵注射液高剂量组和低剂量组均出现过敏反应,其他组均未出现过敏反应。主动过敏试验双黄连注射液有4只动物过敏反应弱阳性,清开灵注射液高剂量组有1只动物过敏反应弱阳性。结论:对于双黄连注射液、清开灵注射液2种注射液而言,临床用药前均应做皮肤被动过敏试验。
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| 关 键 词： | 双黄连注射液 清开灵注射液 复方丹参注射液 皮肤被动过敏性试验 全身主动过敏试验 |
Experimental Study on Allergy of Three Common TCM Injections |
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| Wang Zengxian,Wu Minxia,Gao Xiaofeng,Li Yanli,Wang Mingjun,Li Ping.Experimental Study on Allergy of Three Common TCM Injections[J].Journal of Shanxi College of Traditional Chinese Medicine,2011,12(4):5-7. |
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| Authors: | Wang Zengxian Wu Minxia Gao Xiaofeng Li Yanli Wang Mingjun Li Ping |
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| Institution: | Wang Zengxian,Wu Minxia,Gao Xiaofeng,Li Yanli,Wang Mingjun,Li Ping(Shanxi Biological Application Vocational Technical College,Taiyuan shanxi 030031) |
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| Abstract: | Objective:To observe skin allergy,general allergical reaction effect of Shuanghuanglian injection,Qingkailing injection and compound Danshen injection on rats,guinea pig respectively.Methods:Passive cutaneous anaphylaxis(PCA) and ASA were carried out to study the allergy of three kinds of injections of TCM.Result:The rats exhibited allergic reaction in Shuanghuanglian injection group,Qingkailing injection high dose group and low dose group during PCA test.Weak reactions of Shuanghuanglian and Qingkailing in... |
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| Keywords: | shuanghuanglian injection qingkailing injection compound Danshen injection PCA ASA |
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