| 左乙拉西坦添加治疗难治性癫癎的疗效和安全性分析 |
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| 引用本文： | 丁伯君,邓艳春,张文娟.左乙拉西坦添加治疗难治性癫癎的疗效和安全性分析[J].中国临床神经科学,2011,19(2):189-191,198. |
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| 作者姓名： | 丁伯君 邓艳春 张文娟 |
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| 作者单位： | 第四军医大学附属西京医院神经内科,710032 |
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| 摘 要： | 目的:探讨左乙拉西坦添加治疗难治性癫痫的疗效和安全性。方法:回顾性分析了35例左乙拉西坦添加治疗的难治性癫痫患者,随访3～18个月,观察其疗效及不良反应。结果:左乙拉西坦添加治疗难治性癫痫总有效率为48.6%,对部分性发作和全面性发作的疗效无显著差异。不良反应发生率为31.5%,无严重不良反应。结论:左乙拉西坦是一种安全有效的难治性癫痫治疗药物,可以用于难治性癫痫的添加治疗。
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| 关 键 词： | 左乙拉西坦 难治性癫癎 抗癫癎药 |
Effectiveness and Tolerability of Levetiracetam as Adjunctive Therapy for Refractory Epilepsy |
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| DING Bo-Jun,DENG Yan-Chun,ZHANG Wen-Juan.Effectiveness and Tolerability of Levetiracetam as Adjunctive Therapy for Refractory Epilepsy[J].Chinese Journal of Clinical Neurosciences,2011,19(2):189-191,198. |
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| Authors: | DING Bo-Jun DENG Yan-Chun ZHANG Wen-Juan |
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| Institution: | DING Bo-Jun,DENG Yan-Chun,ZHANG Wen-Juan Department of Neurology,Xi Jing Hospital,the Fourth Military Medical University,Xi'an 710032,China |
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| Abstract: | Aim:To evaluate the efficacy and safety of levetiracetam(LEV) as adjunctive therapy for refractory epilepsy.Methods:35 patients with refractory epilepsy who received treatment with levetiracetam and were followed up for 3 to 18 months were retrospectively reviewed.And curative or adverse effects was observered.Results:48.6%patients had more man 50%reduction in seizures frequency,and the difference of efficacy between focal and generalized seizures was not statistically significant.31.5%patients were reporte... |
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| Keywords: | levetiracetam refractory epilepsy antiepileptic drugs |
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