| 53种抗癫癎中成药的成分分析 |
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| 引用本文： | 马春来,洪震,焦正,施孝金,钟明康.53种抗癫癎中成药的成分分析[J].中国临床神经科学,2011,19(2):146-149. |
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| 作者姓名： | 马春来 洪震 焦正 施孝金 钟明康 |
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| 作者单位： | 1. 复旦大学附属华山医院,临床药学室,200040
2. 复旦大学附属华山医院,神经内科,200040 |
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| 摘 要： | 目的：检测部分抗癫痫中成药中是否含有西药抗癫痫药物的成分。方法：用高效液相色谱法测定53种抗癫痫中成药中是否含有苯巴比妥、苯妥英钠、卡马西平和丙戊酸钠。结果：83.01%中成药中测出含有苯巴比妥、苯妥英钠、卡马西平和丙戊酸。结论：市场上大量未标明含有抗癫痫西药成分的中成药,严重影响癫痫用药安全。
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| 关 键 词： | 抗癫癎药 中药 癫癎 |
Indentification of 53 Species Antiepileptic Chinese Traditional Medicine |
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| MA Chun-Lai,HONG Zhen,JIAO Zheng,SHI Xiao-Jin,ZHONG Ming-Kang.Indentification of 53 Species Antiepileptic Chinese Traditional Medicine[J].Chinese Journal of Clinical Neurosciences,2011,19(2):146-149. |
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| Authors: | MA Chun-Lai HONG Zhen JIAO Zheng SHI Xiao-Jin ZHONG Ming-Kang |
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| Institution: | MA Chun-Lai,HONG Zhen,JIAO Zheng~1,SHI Xiao-Jin~1,ZHONG Ming-Kang~1 1 Clinical Pharmacy Laboratory,2 Department of Neurology,Huashan Hospital,Fudan University,Shanghai 200040,China |
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| Abstract: | Aim:To determine the components of the antiepileptic drugs(AEDs) in some Chinese traditional medicine.Methods:The elements of phenbarbital(PB),phenytoin(PHT),carbamazepine(CBZ) and valproate sodium(VPA) in 53 species for Chinese traditional medicine were measured by HPLC.Results:The AEDs were found in 83.01%of the Chinese traditional medicine.Conclusion:The unmarked components of AEDs in the Chinese traditional medicine have seriously influenced therapeutic efficacy and safety. |
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| Keywords: | antiepileptic drugs Chinese traditional medicine epilepsy |
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