| 冠心病患者高迁移率族蛋白1的表达与意义 |
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| 引用本文： | 刘敏,杨俊,李莉,丁家望,李书国,刘阳. 冠心病患者高迁移率族蛋白1的表达与意义[J]. 中国老年学杂志, 2011, 31(7) |
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| 作者姓名： | 刘敏 杨俊 李莉 丁家望 李书国 刘阳 |
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| 作者单位： | 三峡大学第一临床医学院,宜昌市中心医院心内科,湖北,宜昌,443003 |
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| 基金项目： | 湖北省科技厅自然科学项目 |
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| 摘 要： | 目的 探讨冠心病患者危险程度与血清高迁移率族蛋白B1 (HMGB1)的相关性.方法 ELISA法检测冠心病患者及健康对照人群血清HMGB1蛋白水平.结果 急性冠脉综合征(ACS)患者中HMGB1蛋白水平明显高于稳定型心绞痛(SAP)患者(P<0.05)及健康对照人群(P<0.05),SAP患者HMGB1蛋白水平明显高于健康对照人群(P<0.05).结论 血清HMGB1水平可作为评价冠心病危险程度的指标之一.
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| 关 键 词： | 冠状动脉疾病 高迁移率族蛋白B1 |
Expression and significance of high mobility group box 1 in patients with coronary heart disease |
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| LIU Min,YANG Jun,LI Li,et al.. Expression and significance of high mobility group box 1 in patients with coronary heart disease[J]. Chinese Journal of Gerontology, 2011, 31(7) |
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| Authors: | LIU Min YANG Jun LI Li et al. |
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| Affiliation: | LIU Min,YANG Jun,LI Li,et al.Department of Cardiology,the First Clinical Medical College,Sanxia University,Yichang Central Hospital,Yichang 443003,Hubei,China |
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| Abstract: | Objective To explore the correlation between the risk of coronary heart disease(CHD) and serum high mobility group box 1(HMGB1).Methods ELISA was used to detect the serum HMGB1 protein levels of CHD patients and healthy control group patients.Results HMGB1 protein levels in patients with acute coronary syndrome(ACS) was significantly higher than that of stable angina(SAP) patients and healthy control subjects,patients with SAP HMGB1 protein levels were significantly higher than that of healthy people.Conclu... |
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| Keywords: | Coronary heart disease High mobility group box 1 |
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