| 2型糖尿病患者胰岛素样生长因子-2与骨密度的关系 |
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| 引用本文： | 隋春华,陈奕,余娇,赵丽娟,陈鑫,陆颖理. 2型糖尿病患者胰岛素样生长因子-2与骨密度的关系[J]. 中国临床医学, 2011, 18(2): 196-197 |
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| 作者姓名： | 隋春华 陈奕 余娇 赵丽娟 陈鑫 陆颖理 |
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| 作者单位： | 上海交通大学医学院附属第九人民医院内分泌科,上海,200011 |
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| 摘 要： | 目的：研究2型糖尿病患者病程、空腹C肽水平、骨密度与血清胰岛素样生长因子-2（IGF-2）的关系。方法：96例2型糖尿病患者,均测量身高、体质量、骨密度、骨密度以及空腹血清C肽和IGF-2水平。分析糖尿病病程、IGF-2、骨量以及空腹C肽水平之间的关系。结果：随着糖尿病病程延长,IGF-2水平下降;随着骨密度水平下降,IGF-2水平下降;随着空腹C肽水平下降,IGF-2水平下降。结论：IGF-2可能参与了2型糖尿病的进程和骨质疏松的发生。
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| 关 键 词： | 2型糖尿病 胰岛素样生长因子-2 C肽 骨质疏松 |
Relationship between Insulin-Like Growth Factor 2 (IGF-2) and Bone Mineral Density in Patients with Type2 Diabetes |
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| SUI Chunhua,CHEN Yi,YU Jiao,ZHAO Lijuan,CHEN Xin,LU Yingli. Relationship between Insulin-Like Growth Factor 2 (IGF-2) and Bone Mineral Density in Patients with Type2 Diabetes[J]. Chinese Journal Of Clinical Medicine, 2011, 18(2): 196-197 |
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| Authors: | SUI Chunhua CHEN Yi YU Jiao ZHAO Lijuan CHEN Xin LU Yingli |
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| Affiliation: | ( Department of Endocrinology,the Ninth People＇s Hospital,Shanghai Jiaotong University Medical School,Shanghai 200011,China ) |
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| Abstract: | Objective：To study the relationship between the serum level os insulin-like growth factor 2（IGF-2） and bone mineral density（BMD） in patients with type2 diabetes（DM）.Methods：Height,weight,fasting serum C-peptide,IGF-2,and BMD were measure in 96 patients with DM.The associations among the levels of IGF-2,C-peptide and BMD were analyzed.Results：As the years of being DM gets longer,the level of IGF-2 gets lower.BMD was positively related with the lever of IGF-2.When the level of C-peptide decreased,the level of IGF-2 tended to be lower.Conclusions：IGF-2 may contribute to the DM outbreak and the occurrence of osteoporosis. |
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| Keywords: | Type 2 diabetes Insulin-like growth factor 2 C-peptide Osteoporosis |
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