| 参芪扶正注射液对老年进展期胃癌患者免疫功能及临床疗效的影响 |
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| 引用本文： | 刘宏,韩冬. 参芪扶正注射液对老年进展期胃癌患者免疫功能及临床疗效的影响[J]. 中国临床药理学杂志, 2011, 27(3) |
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| 作者姓名： | 刘宏 韩冬 |
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| 作者单位： | 1. 北京市丰台区铁营医院中医科,北京,100079
2. 北京市中医医院肿瘤科,北京,100010 |
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| 摘 要： | 目的 观察老年进展期胃癌患者化疗加用参芪扶正注射液(免疫增强中药制剂)治疗后免疫功能变化与临床疗效.方法 85例患者随机分为2组,对照组用FOLFOX4化疗方案;而治疗组在化疗方案的基础上,加用参芪扶正注射液治疗,比较治疗前后外周血T细胞亚群及NK细胞的水平.结果 在化疗第1,2周期后,治疗组的外周血T细胞亚群、NK细胞等检测值均较治疗前明显增高(P<0.05);在生活质量与临床症状的改善、不良反应等,较对照组有显著性差异(P<0.05).结论 参芪扶正注射液能够显著改善老年进展期胃癌患者的机体免疫功能状态,提高生活质量.
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| 关 键 词： | 参芪扶正注射液 胃癌 免疫功能 |
Effects of Shenqifuzheng injection on the immunolologic function and clinic efficacy in the elderly patients with advanced gastric cancer |
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| LIU Hong,HAN Dong. Effects of Shenqifuzheng injection on the immunolologic function and clinic efficacy in the elderly patients with advanced gastric cancer[J]. The Chinese Journal of Clinical Pharmacology, 2011, 27(3) |
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| Authors: | LIU Hong HAN Dong |
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| Affiliation: | LIU Hong1,HAN Dong2(1.Department of Traditional Chinese Medicine,Tieying Hospital of Fengtai District,Beijing 100079,China,2.Department of Oncology,Beijing Hospital of Traditional Chinese Medicine,Beijing 100010,China) |
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| Abstract: | Objective To investigate the changes of T-lymphocyte subsets,NK cells,and clinical effects in elderly patients with advanced gastric cancer after the treatment of chemotherapy and Shenqifuzheng injection.Methods Eighty-five cases were individed in two groups.Treatment group was treated by Shenqifuzheng injection followed the basis of FOLFOX4 chemotherapy treatment,while control group was treated by FOLFOX4 chemotherapy.The blood T-lymphocyte subsets and NK cells was compared between two groups.Results After... |
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| Keywords: | Shenqifuzheng injection gastric cancer immunolologic function |
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