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瘦素对小鼠胚胎体外发育的影响
引用本文:刘继龙. 瘦素对小鼠胚胎体外发育的影响[J]. 中国妇幼保健, 2012, 27(28): 4452-4453
作者姓名:刘继龙
作者单位:广西钦州市妇幼保健院生殖中心 535000
摘    要:目的:探讨瘦素在体外对小鼠胚胎发育的影响。方法:将受精后的2-细胞胚胎分别置于含不同剂量瘦素的培养液中进行体外培养观察胚胎发育情况。结果:瘦素能提高2-细胞胚胎体外发育的发育率,当瘦素剂量为50 ng/ml时各期发育率最好。结论:瘦素参与了小鼠胚胎的发育,能提高胚胎发育率。

关 键 词:小鼠  瘦素  胚胎  体外发育

Effect of leptin on embryonic development of mice in vitro
LIU Ji-Long. Effect of leptin on embryonic development of mice in vitro[J]. Maternal and Child Health Care of China, 2012, 27(28): 4452-4453
Authors:LIU Ji-Long
Affiliation:LIU Ji-Long.Reproductive Center,Qinzhou Maternal and Child Health Hospital,Qinzhou 535000,Guangxi Zhuang Autonomous Region,China
Abstract:Objective:To explore the effect of leptin on embryonic development of mice in vitro.Methods:Fertilized two-cell embryos were treated in culture solutions containing different doses of leptin,then the development of embryos was observed in vitro.Results:Leptin improved the developmental rate of two-cell embryos in vitro,the developmental rates during different periods were the highest when the dose of leptin was 50 ng/ml.Conclusion:Leptin is involved in embryonic development of mice,which can improve the developmental rate of embryos.
Keywords:Mouse  Leptin  Embryo  Development in vitro
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