已婚妇女子宫颈人乳头状瘤病毒感染危险因素Logistic回归分析

目的:探讨已婚妇女子宫颈人乳头状瘤病毒(HPV)感染的相关危险因素。方法:根据妇科常规检查及病理学检查结果,将3 600例已婚妇女分为有宫颈HPV感染380例和未有宫颈HPV感染3 220例,应用非条件Logistic回归分析分别进行单因素和多因素分析。结果:单因素分析结果表明,两组间年龄≥30岁、初次性生活年龄<20岁、孕次≥2次、性伴侣≥2个、受教育≥12年、使用避孕套的差异有统计学意义(P<0.05),其中年龄≥30岁、初次性生活年龄<20岁、孕次≥2次、性伴侣≥2个、受教育≥12年与已婚妇女宫颈HPV感染的发生呈正相关(P<0.05);使用避孕套与已婚妇女宫颈HPV感染的发生呈负相关(P<0.05)。进一步行多因素分析结果表明,受教育≥12年、性伴侣≥2个是已婚妇女宫颈HPV感染发生的独立危险因素(P<0.05),使用避孕套是已婚妇女宫颈HPV感染发生的保护因素。结论:文化程度越高及性伴侣越多的已婚妇女,可以明显增加宫颈HPV感染的风险,而使用避孕套可以有效降低宫颈HPV感染的发生,因此对高危人群需进行必要的健康教育,并定期进行宫颈疾病筛查。

Logistic regression analysis about the risk factors of cervical HPV infection of the married women

Objective:To study the risk factors of cervical human papilloma virus(HPV) infection of the married women.Methods:According to the conventional check and pathology gynecological examination,380 cases were infected by cervical HPV and 3220 cases were not infected by cervical HPV in 3600 married women.They were analyzed by logistic regression analysis.Results:Single factor analysis results shown that: the differences about age≥30 years old,age of the first sex act< 20 years old,pregnancy times≥2,sexual partner≥2,education year≥12 years and using frequency of condom were statistical significance between the two groups(P<0.05).Among them,age≥30 years old,age of the first sex act< 20 years old,pregnancy times≥2,sexual partner≥2,education year≥12 years related positively with cervical HPV infection of married women(P<0.05).Using frequency of condom related negatively with cervical HPV infection of married women(P<0.05).Further more factors analysis results shown that: education year≥12 years and sexual partner≥2 were the independent risk factors of cervical HPV infection of married women(P<0.05),using frequency of condom was protection factor of cervical HPV infection of married women.Conclusion:The higher the education level of married women is and the more the sexual partners of married women is,the higher the risk of cervical HPV infection is,and using a condom can effectively reduce the occurrence of cervical HPV infection,so it is necessary to undertake health education and regular cervical disease screening for high-risk groups.