| 中小学生HBV感染状况调查及痘苗重组DNA乙肝疫苗免疫效果初步观察 |
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| 引用本文： | 周玲 韩亚茹. 中小学生HBV感染状况调查及痘苗重组DNA乙肝疫苗免疫效果初步观察[J]. 中国学校卫生, 1993, 14(3): 157-158 |
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| 作者姓名： | 周玲 韩亚茹 |
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| 作者单位： | 南京医学院，南京医学院，南京医学院，南京医学院，卫生部北京生物制品研究所，卫生部北京生物制品研究所，卫生部北京生物制品研究所，卫生部北京生物制品研究所，南京市玄武区卫生防疫站，南京市玄武区卫生防疫站，南京市玄武区卫生防疫站，南京市玄武区卫生防疫站 210029，210029，210029，210029 |
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| 摘 要： |
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| 关 键 词： | 感染率 DNA 乙型肝炎 疫苗 阳转率 |
Studies on HBV Infection end Effect of Hepatitis B Vaccination with Recombinant Vaccinia Virus among Middle School Students and Pupils |
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| /Zhou Ling,et al.. Studies on HBV Infection end Effect of Hepatitis B Vaccination with Recombinant Vaccinia Virus among Middle School Students and Pupils[J]. Chinese Journal of School Health, 1993, 14(3): 157-158 |
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| Authors: | /Zhou Ling et al. |
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| Abstract: | Blood specimens from 808 middle school students and pupils were detected for HBV-M in June, 1991. The infection rate was 40. 84%. The positivity rates of HBsAg,anti-HBs and anti-HBc were 4.33% ,25.37% and 33.94% ,respectively. Of 330 HBV infected subjects,83.94% were anti-HBc positive,while 10.61% HBsAg positive, when anti-HBc and anti-HBs were detected in combination, 99.39% of HBV infected subjects were found. Among 49 anti-HBs positive subjects, 59.18% effected autoimmune protection. Recombinant vaccinia virus prepared in Beijing was applied to immunize 223 HBV-M negative subjects. Seroconvertion rates of anti-HBs in vaccinated subjects were 46.64% and 98.65% for one and three months after the initial vaccination. |
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| Keywords: | HBV infection recombinant vaccinia virus seroconvertion rate of anti-HBs |
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