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The Clonal Expansion Dynamics of the HIV-1 Reservoir: Mechanisms of Integration Site-Dependent Proliferation and HIV-1 Persistence
Authors:Yang-Hui Jimmy Yeh  Kerui Yang  Anya Razmi  Ya-Chi Ho
Institution:Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06519, USA; (Y.-H.J.Y.); (K.Y.); (A.R.)
Abstract:
Keywords:HIV-1 latent reservoir  HIV-1 cure  clonal expansion  HIV-1 insertional mutagenesis  HIV-1 integration site-dependent proliferation  aberrant HIV-1 RNA splicing  persistent nonsuppressible low-level viremia  HIV-1 proviral landscape  immune selection pressure  HIV-1 suppressing agents
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