| 预处理对O_3衰老模型超氧化物歧化酶活性的影响 |
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| 引用本文： | 陈友琴,何杰,胡新珉,刘鸿莲,幸浩洋.预处理对O_3衰老模型超氧化物歧化酶活性的影响[J].中国医学物理学杂志,2000(2). |
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| 作者姓名： | 陈友琴 何杰 胡新珉 刘鸿莲 幸浩洋 |
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| 作者单位： | 华西医科大学基础医学院物理教研室!四川成都610044(陈友琴，胡新珉，刘鸿莲，幸浩洋)，成都市第三人民医院外科!成都610031(何杰) |
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| 摘 要： | 为了确定预处理对小鼠 O3致衰老模型是否具有保护作用 ,本研究利用 SOD微量快速测定法 ,检测和分析了经云南花粉田七口服液 (Yun Nan Pollen Tienchi Oral L iquid,简称 YN- PTOL )预处理后小鼠全血和心肌中超氧化物歧化酶 (superoxide dismutase,SOD)的活性 ,结果显示 :预处理实验组 SOD活性明显高于空白对照组和阳性对照组 (P<0 .0 5 ) ,同时 ,空白对照组与阳性对照组之间无显著性差异。这表明 :YN- PTOL预处理能改善或提高 O3致老小鼠模型机体内 SOD活性 ,是一种有应用前景的延缓衰老的保健药物。
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| 关 键 词： | 超氧化物歧化酶 臭氧 衰老 预处理 |
Protective effect of preconditioning with yunnan pollen tiench oral liquid on the activity of superoxide dismutase in mouse |
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| CHEN You-qin ,HE Jie ,HU Xin-min ,LIU Hong-lian ,XING Hao-yang WTBX.Protective effect of preconditioning with yunnan pollen tiench oral liquid on the activity of superoxide dismutase in mouse[J].Chinese Journal of Medical Physics,2000(2). |
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| Authors: | CHEN You-qin HE Jie HU Xin-min LIU Hong-lian XING Hao-yang [WTBX] |
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| Institution: | CHEN You-qin 1,HE Jie 2,HU Xin-min 1,LIU Hong-lian 1,XING Hao-yang 1 [WT6BX] |
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| Abstract: | To investigate whether preconditioning have protective effect on aging model against oxidative damage from free radical, the activity of superoxide dismutase of plasma and myocardium was determined by SOD rapidly assay. The results showed that the experimental group had a higher SOD status than other groups (P<0.05). Meanwhile, the amount of SOD was no significant between the blank group and the positive group (P>0.05). It is evident that the precondintioning with YN-PTOL can increase or improve the activity of SOD in mouse. |
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| Keywords: | superoxide dismutase ozone aging preconditioning |
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