有否静脉溶栓的急性心肌梗死63例尸解病理分析

探讨溶栓治疗的并发症。方法急性心肌梗死住院死亡并行尸体解剖６３例，２６例曾给予溶栓治疗，３７例行常规治疗。结果两组性别、年龄、ＣＨＤ的危险因素，梗死次数，心肌酶学、梗死部位及血管狭窄程度均无明显差异。结论ＡＭＩ早期溶栓治疗心脏破 发生率较非溶栓组明显升高。

An autopsy pathological analysis of 63 cases with acute myocardial infarction with or without thrombolysis

AIM To analyze complications of acute myocardial infarction with or without thrombolysis. METHODS 63 cases with acute myocardial infarction (AMI) were examined by autopsy, 26 of whom had undergone thromobolytic therapy and 37 routine treatment. RESULTS The two groups had no difference in sex, age, risk factors of CHD, times and sections of infarction, serum creatine kinase and the narrowing degree of vessels ( P >0.05). The myocardial hemorrhage in non thrombolysis group was much higher than that in thrombolysis group and the cardiac rupture in thrombolysis was also higher than that in non thrombolysis group ( P < 0.05 ). CONCLUSION Compared with AMI without thrombolysis, the incidence of cardiac rupture from AMI treated with thrombolysis is higher in the early stage, but not other complications such as single myocardial hemorrhage and infarction size expanding. The hemorrhage and cardiac rupture are associated with the severity of narrowing vessels.