空腹血糖受损相关影响因素分析

目的探讨空腹血糖受损（IFG）的相关影响因素。方法对2008年在我院体检的2517例人员进行病史询问，做身高、体重、血压、空腹血糖、血脂的测量，根据空腹血糖值分为空腹血糖正常（NFG）组和空腹血糖受损（IFG）组并对其资料进行统计学分析。结果腹血糖受损的患病率为26．6％。IFG患病率随年龄的增加而增高，男性IFG患病率高于女性。空腹血糖受损组与空腹血糖正常组的体重指数（BMI）、收缩压（SBP）、舒张压（DBP）、血糖、甘油三酯（TG）、总胆固醇（TC）、高密度脂蛋白胆固醇（HDL—C）、低密度脂蛋白胆固醇（LDL—C）的差异均有统计学意义（P〈0．05）。IFG组具有两项及以上心血管危险因素聚集的相对危险度是NFG组的2．232倍（P=0．000，95％CI1．852—2．689）。进入logistic回归模型的有BMI、年龄、DBP、TG、糖尿病家族史。结论IFG患者已开始使心血管危险因素聚集，且他们的发病率与年龄、超重肥胖、血压、血脂代谢异常、糖尿病家族史相关。

Analysis of risk factors impaired fasting glucose

Objective To investigate the influencing factors of the impaired fasting glucose （IFG）. Methods 2517 cases, 1807 males and 710 females, aged 24 -91 years, mean age of 48.7 ± 10.9 years, who visited medical examination in 2008 were enrolled into this study. Their medical history, height, weight, blood pressure, fasting blood glucose, blood lipids and fasting blood glucose were detected and analyzed statistically. According to fasting blood glucose divided into the normal fasting glucose （NFG） and impaired fasting glucose groups. Results The prevalence of impaired fasting glucose was 26.6%, and the prevalence rate of IF（; in males was more than those in females. IFG prevalence rate increased with age. The differences of BMI, SBP, DBP, blood glucose, TG, TC, HDL - C, LDL - C between the normal fasting glucose group and the IFG group were statistically significant （P 〈0.05）. Odds ratio for two and over cardiovascular risk factors in IFG group was 2.232 times （P =0. 000, 95% CI1. 852 -2. 689） versus NFG group. BMI, age, DBP, TG, family history of diabetes entered into the logistic regression model. Conclusion People with IFG show the clustering of cardiovascular risk factors and it is related with overweight and obesity, age, blood pressure, disorders of lipid metabolism and family history of diabetes.