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Ectopic pregnancy
Affiliation:1. Instituto Maimónides de Investigación Biomédica de Cordoba (IMIBIC), Cordoba, Spain;2. Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain;3. Hospital Universitario Reina Sofia, Cordoba, Spain;4. CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Cordoba, Spain;5. Instituto Valenciano de Infertilidad (IVI), University of Valencia, Valencia, Spain;6. Instituto de Investigación Sanitaria Hospital Clínico de Valencia INCLIVA, Valencia, Spain;7. Department of Applied Mathematics-I, University of Seville, Seville, Spain;8. Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain;9. IVI-Sevilla, Sevilla, Spain;10. Department of Investigative Medicine, Imperial College London, United Kingdom;11. Institute of Biomedicine, University of Turku, Turku, Finland
Abstract:Ectopic Pregnancy (EP) occurs in around 1–2% of all pregnancies, and is associated with significant morbidity and mortality. Over 98% implant in the Fallopian tube. The mainstay of diagnosis is by transvaginal ultrasound supported by serial serum human chorionic gonadotrophin (hCG) measurements. Management of tubal EP has moved away from surgery with growing experience with medical (methotrexate) and expectant management for selected women. Surgery will always have a role in the management of women with EP who are acutely unwell or where medical management is unlikely to be, or has already been unsuccessful. Ultrasound diagnostic criteria for non-tubal EP have been established and these cases are best managed on an individual basis. Future areas of improvement include the critical need to teach healthcare professionals to consider pregnancy related causes of collapse in all women of reproductive age.
Keywords:ectopic pregnancy  heterotropic pregnancy  human chorionic gonadotrophin  laparoscopy  methotrexate  salpingectomy  salpingotomy
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