Reproductive and Obstetric Outcomes After Hysteroscopic Removal of Retained Products of Conception |
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Affiliation: | 1. Endometriosis Section, Gynecologic Division, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil (Drs. Abrão, Andres, and Barbosa);2. Gynecologic Division, BP–A Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Brazil (Drs. Abrão, Andres, and Bassi);3. Benign Gynecology Surgery Section, Department of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, Ohio (Dr. Kho).;1. Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee-Womens Hospital of UPMC, Pittsburgh, Pennsylvania (Drs. Melnyk, Rindos, and Lee);2. Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania (Dr. Khoudary);1. Advanced Gynecologic Surgery Institute, Chicago, Illinois (Drs. Cholkeri-Singh and Miller);2. Russell Institute for Research & Innovation at Advocate Health Systems, Park Ridge, Illinois (Ms. Zamfirova). |
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Abstract: | Study ObjectiveTo evaluate the reproductive outcomes in women treated for retained products of conception (RPOC) by hysteroscopy (morcellation vs loop resection).DesignCohort study.SettingA teaching and university hospital.PatientsPatients included in a previous randomized controlled trial on hysteroscopic removal of RPOC comparing morcellation (n = 46) with loop resection (n = 40).InterventionsHysteroscopic morcellation versus loop resection.Measurements and Main ResultsThe primary outcome measures were live birth and pregnancy complications (including abnormal placentation [placenta accreta/increta/percreta], placenta previa, vasa previa, retained placenta after delivery or incomplete expulsion with the need for manual removal or curettage, and RPOC), uterine rupture, and other complications (blood loss, preterm labor, preterm premature rupture of membranes, hypertensive disorders of pregnancy, and intrauterine growth restriction). The live birth rate was 88.9% in the morcellation group and 68.2% in the loop resection group (p = .09). Uterine rupture occurred in 1 patient in the morcellation group (4.2%) (p = 1.00). Placental complications were found in 20.8% and 22.2% of the hysteroscopic morcellation and loop resection groups, respectively (p = .33), and other pregnancy complications were seen in 33.3% and 16.6% of the 2 groups (p = .33). The secondary outcome was time to pregnancy. The median time to pregnancy was 14 weeks (interquartile range [IQR], 5–33 weeks) in the morcellation group and 15 weeks (IQR, 6–37 weeks) in the loop resection group (p = .96).ConclusionHysteroscopic removal of RPOC seems to have no detrimental effect on reproductive outcome and no significant effect on pregnancy rate. |
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