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Post-Myocardial Infarction Ventricular Septal Defect: A Comprehensive Review
Institution:1. Division of Cardiac Surgery, University of Florida, Gainesville, Florida;2. Division of Cardiac Surgery and Heart and Vascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania;3. Division of Cardiac Surgery, Penn State University, Hershey, Pennsylvania;4. Outcomes Research and Assessment Group, Duke Clinical Research Institute, Chapel Hill, North Carolina;5. Department of Surgery, Duke University School of Medicine, Chapel Hill, North Carolina;6. Shands Jacksonville, University of Florida, College of Medicine-Jacksonville, Jacksonville, Florida;7. Division of Cardiac Surgery, Johns Hopkins All Children''s Heart Institute, St. Petersburg, Florida;1. Department of Intensive Care, St Andrew''s War Memorial Hospital, Brisbane, Qld, Australia;2. Cardiothoracic Surgery and Transplantation, The Alfred Hospital, Melbourne, Vic, Australia;3. Department of Intensive Care, Gold Coast University Hospital, Gold Coast, Qld, Australia;4. Department of Cardiothoracic Surgery, The Prince Charles Hospital, Brisbane, Qld, Australia;5. Department of Cardiothoracic Surgery, The Princess Alexandra Hospital, Brisbane, Qld, Australia;6. Department of Cardiothoracic Surgery, The Royal Prince Alfred Hospital, Sydney, NSW, Australia;7. Department of Intensive Care, The Prince Charles Hospital, Brisbane, Qld, Australia;1. Interventional Cardiology, Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston;2. Cardiovascular Division, University of Miami, Miller School of Medicine, Fla;3. Department of Pediatrics, Texas Tech University Health Sciences Center, Lubbock;4. Division of Cardiology, Henry Ford Hospital, Detroit, Mich
Abstract:Post-myocardial infarction (MI) ventricular septal defect (VSD) is a rare but potentially catastrophic mechanical complication that occurs in <1% of patients following a myocardial infarction and it is associated with a high morbidity and mortality despite improvements in medical and surgical therapies. Post-MI VSD is a medical emergency and outcome is very poor in medically treated patients. Treatment of choice remains surgical closure of defect and transcatheter defect closure less so. We performed a comprehensive review of the clinical presentation and management options of post-MI VSD.
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