Ocular allergy treatment comparisons: Azelastine and olopatadine |
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Authors: | Leonard Bielory Praveen Buddiga Stephen Bigelson |
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Affiliation: | (1) Department of Medicine & Pediatric Ophthalmology, UMDNJ-New Jersey Medical School, 90 Bergen Street, DOC Suite 4700, 07103 Newark, NJ, USA |
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Abstract: | Azelastine hydrochloride 0.05% and olopatadine hydrochloride 0.1% are topical ocular allergy treatments that have demonstrated multiple pharmacologic actions, including antihistamine, mast cell stabilization, and inhibition of proinflammatory mediators. In this article, the mechanisms of action, efficacy, and tolerability of these two agents on ocular signs and symptoms are examined. By studying the various target sites of drug action, an enhanced clinical response algorithm of these topical ocular agents can be implemented to maximize the response for patients suffering from ocular allergy. |
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