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Investigation of the direct effects of salmon calcitonin on human osteoarthritic chondrocytes
Authors:Bodil-Cecilie Sondergaard  Suzi H Madsen  Toni Segovia-Silvestre  Sarah J Paulsen  Thorbjorn Christiansen  Christian Pedersen  Anne-Christine Bay-Jensen  Morten A Karsdal
Affiliation:1. Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Keele, Staffs ST5 5BG, UK
Abstract:

Background

Regional musculoskeletal pain such as back or shoulder pain are commonly reported symptoms in the community. The extent of consultation to primary care with such problems is unknown as a variety of labels may be used to record such consultations. The objective was to classify musculoskeletal morbidity codes used in routine primary care by body region, and to determine the annual consultation prevalence of regional musculoskeletal problems.

Methods

Musculoskeletal codes within the Read morbidity Code system were identified and grouped by relevant body region by four GPs. Consultations with these codes were then extracted from the recorded consultations at twelve general practices contributing to a general practice consultation database (CiPCA). Annual consultation prevalence per 10,000 registered persons for the year 2006 was determined, stratified by age and gender, for problems in individual regions and for problems affecting multiple regions.

Results

5,908 musculoskeletal codes were grouped into regions. One in seven of all recorded consultations were for a musculoskeletal problem. The back was the most common individual region recorded (591 people consulting per 10,000 registered persons), followed by the knee (324/10,000). In children, the foot was the most common region. Different age and gender trends were apparent across body regions although women generally had higher consultation rates. The annual consultation-based prevalence for problems encompassing more than one region was 556 people consulting per 10,000 registered persons and increased in older people and in females.

Conclusions

There is an extensive and varied regional musculoskeletal workload in primary care. Musculoskeletal problems are a major constituent of general practice. The output from this study can be used as a resource for planning future studies.
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