| 半枝莲的化学成分 |
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| 引用本文： | 李宁,肖海涛,孟大利,王金辉,李铣. 半枝莲的化学成分[J]. 中药研究与信息, 2009, 0(12): 16-17,20 |
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| 作者姓名： | 李宁 肖海涛 孟大利 王金辉 李铣 |
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| 作者单位： | 沈阳药科大学中药学院,辽宁沈阳110016 |
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| 摘 要： | 目的：对黄芩属植物半枝莲Scutellaria barbataD．Don全草的抗肿瘤活性部位（三氯甲烷萃取物）的化学成分进行分离、鉴定。方法：采用反复硅胶、LH-20葡聚糖凝胶等柱色谱方法进行分离纯化，并通过理化常数测定与谱学分析鉴定其化学结构。结果：得到7个化合物，分别鉴定为木犀草素（1），柚皮素（2）、半枝莲酸（3），2，4-二羟基苯甲酸（4），香豆酸乙酯（5），β-谷甾醇（6），胡萝卜苷（7）。结论：化合物4、5为首次从半枝莲中分离得到。
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| 关 键 词： | 半枝莲 抗肿瘤活性部位 化学成分 |
Chemical Constituents of Scutellaria barbata D. Don. |
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| Li Ning,Xiao Haitao,Meng Dali,Wang Jinhui,Li Xi. Chemical Constituents of Scutellaria barbata D. Don.[J]. Research & Information on Traditional Chinese Medicine, 2009, 0(12): 16-17,20 |
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| Authors: | Li Ning Xiao Haitao Meng Dali Wang Jinhui Li Xi |
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| Affiliation: | an (School of Traditional Chinese Material Medica, Shenyang Pharmaceutical University, Shenyang Liaoning 110016, China) |
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| Abstract: | Objective： To study the chemical Methods： Compounds were isolated by chromatograph constituents of antitumor active part of Scutellaria barbata D. Don. y on silica gel, Sephadex LH-20 column and identified on the basis of physico-chemical constants and spectral analysis. Results： Seven compounds were obtained and their structures were identified as luteolin （ 1 ）, naringenin （2）, scutellaric acid （3）, 2,4-dihydroxybenzoic acid （4）, p-coumaric acid acetate （5）,β-sitosterol（6）, daucosterol（7）. Conclusion： Compounds 4 and 5 were isolated from S. barbata for the first time. |
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| Keywords: | Scutellaria barbata D. Don. Antitumor active part Chemical constitutents |
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