纯钛表面快速沉积羟基磷灰石涂层的实验研究

目的探讨在纯钛种植体表面快速沉积羟基磷灰石涂层的新方法。方法20片纯钛片均分为A、B两组。A组用H2SO54与HCI混合液酸蚀；B组用H2SO4与HCI混合液酸蚀，再用5mol／L NaOH溶液60℃处理24h后，600℃热处理1h。然后两组试件同时置于仿生液A液和B液中各1天。场发射扫描电子显微镜观察分析涂层的形貌。结果两组试件表面均可沉积致密的羟基磷灰石涂层，涂层由1—3μm的小球组成。X射线衍射分析证实其为碳酸化的羟基磷灰石。结论在纯钛表面可以快速沉积碳酸化的羟基磷灰石。

Experimental study of fast formation of biomimetic apatite coatings on pure titanium surface

OBJECTIVE: To investigate calcium-phosphate coating on commercial pure titanium substrate using a fast biomimetic procedure. METHODS: The titanium specimens were divided into two groups, group A and group B. The specimens of group A were only treated with the mixture of H2SO4/HCl for 30 min. The specimens of group B were treated with the mixture of H2SO4/HCl for 30 min, immersed into 5 mol/L NaOH solution at 60 degrees C for 24 h, and then heated to 600 degrees C and maintained for 1 h. All specimens were soaked into simulated body fluid-A (SBF) and SBF-B for each day. The surface morphology was observed by field scanning electron microscopy. RESULTS: Dense calcium-phosphate coating deposited on all the titanium surfaces of two groups. The calcium-phosphate coating consisted of spheric structure with a diameter of 1 approximately 3 microm, which was proved to be hydroxycarbonated apatite with the analysis of X-ray diffraction. CONCLUSIONS: Thin hydroxycarbonated apatite coating can deposite on pure titanium using a fast biomimetic procedure.