膀胱癌组织中MMP-2与TIMP-2 mRNA的表达及临床意义 |
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作者单位: | Yunyan Wang,Junsong Meng,Haijun Zhuang(Department of Urology, Huai'an No.1 Hospital Affiliated with Nanjing Medical University, Huai'an 223300, China);Jianquan Hou,Duangai Wen(Department of Urology, First Affiliated Hospital of Soochow University, Suzhou 215006, China) |
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摘 要: |
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关 键 词: | 表达 膀胱 临床意义 癌组织 |
Expressions and clinical significances of MMP-2 and TIMP-2 mRNA in bladder transitional cell carcinomas |
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Authors: | Yunyan Wang Junsong Meng Haijun Zhuang Jianquan Hou Duangai Wen |
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Institution: | Yunyan Wang1,Junsong Meng1,Haijun Zhuang1,Jianquan Hou2,Duangai Wen21 Department of Urology,Huai'an No.1 Hospital Affiliated with Nanjing Medical University,Huai'an 223300,China2 Department of Urology,First Affiliated Hospital of Soochow University,Suzhou 215006,China |
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Abstract: | Objective:The aim of the study was to investigate the expressions of matrix metalloproteinase-2(MMP-2) and tissue inhibitor of MMP-2(TIMP-2) mRNA in transitional cell carcinomas of bladder and discuss their clinical significances.Methods:Using RT-PCR and real time quantitative PCR(RQ-PCR) technique,the expressions of MMP-2 and TIMP-2 mRNA of 45 cases of bladder carcinoma(tumor group) and 10 cases of normal bladder tissue(control group) were analyzed.Results:MMP-2 and TIMP-2 were not expressed in control gro... |
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Keywords: | transitional cell carcinoma of bladder matrix metalloproteinase-2(MMP-2) tissue inhibitor of MMP-2(TIMP-2) |
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