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Studies on the antioxidant activity of essential oil and different solvent extracts of Vitex agnus castus L. fruits from Turkey
Authors:Cengiz Sarikurkcu  Kadir Arisoy  Bektas Tepe  Ahmet Cakir  Gulsah Abali  Ebru Mete
Institution:aMugla University, Faculty of Science and Literature, Department of Chemistry, Mugla 48000, Turkey;bCelal Bayar University, Faculty of Science and Literature, Department of Chemistry, Muradiye, Manisa 45030, Turkey;cCumhuriyet University, Faculty of Science and Literature, Department of Molecular Biology and Genetics, Sivas 58140, Turkey;dAtatürk University, Kazım Karabekir Education Faculty, Department of Chemistry, 25240 Erzurum, Turkey;eAtatürk University, Faculty of Arts and Sciences, Department of Chemistry, 25240 Erzurum, Turkey
Abstract:This study is designed to examine the chemical composition and antioxidant activity of the essential oil and different solvent extracts of Vitex agnus castus. GC and GC–MS analysis was resulted in the detection of 27 components, representing 94.5% of the oil. Major components of the oil were 1,8-cineole (24.98%), sabinene (13.45%), α-pinene (10.60%), α-terpinyl acetate (6.66%), and (Z)-β-farnesene (5.40%). Antioxidant activities of the samples were determined by three different test systems, DPPH, β-carotene/linoleic acid and reducing power assays. In all systems, water extract exhibited excellent activity potential than those of other extracts (hexane, dichloromethane, ethyl acetate and methanol) and the oil. As expected, amount of total phenolics was very high in this extract (112.46 ± 1.22 μg GAEs/mg extract). Dichloromethane extract has been found to be rich in flavonoids. A positive correlation was observed between the antioxidant activity potential and total phenolic and flavonoid levels of the extracts.
Keywords:Vitex agnus castus  Antioxidant activity  DPPH  β  -Carotene  Essential oil
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