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Epstein-Barr virus-transformed B cells can present acetylcholine receptor to autologous autoreactive T cells |
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| Authors: | R Hohlfeld M Michels H Tesch A Fahsbender K Heininger B M Conti-Tronconi K V Toyka |
| Abstract: | Epstein-Barr virus- (EBV-)transformed B cells were obtained from a patient with myasthenia gravis, who was also the donor of a T cell line specific for acetylcholine receptor (AChR). After three months of culture, the EBV-transformed B cells could effectively present native membrane-bound AChR to autologous AChR-specific T cells. |
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