MR特征追踪技术评价急性心肌炎患者左心房功能

目的 采用心脏MR特征追踪(CMR-FT)技术定量评估急性心肌炎患者左心房功能改变,分析心房应变参数诊断急性心肌炎的价值.方法 对28例临床诊断急性心肌炎患者(病例组)及26名健康志愿者(对照组)采集CMR电影序列图像,经后处理分析得到左心室功能、左心房容积及应变参数.采用受试者工作特征(ROC)曲线,计算曲线下面积(...

Cardiac MR feature tracking for evaluating left atrial function of acute myocarditis patients

Objective To quantitatively evaluate the changes of left atrial function in acute myocarditis with cardiac MR feature tracking(CMR-FT)technology,and to analyze the value of atrial strain parameters for diagnosis of acute myocarditis.Methods CMR cine imaging were collected from 28 patients with clinically diagnosed acute myocarditis(patient group)and 26 healthy volunteers(control group).The left ventricular function,left atrial volume and strain parameters were obtained with post-processing analysis.Receiver operating characteristic(ROC)curves of parameters being statistically different between groups were drawn,and the corresponding area under the curve(AUC)were calculated to evaluate the diagnostic value of strain parameters of acute myocarditis.Results The left ventricular end-systolic volume index(LVESVI)in patient group was higher than that in control group(P=0.046),while no statistical difference of the other left heart function parameters was found between groups(all P>0.05).Compared with control group,the total left atrial emptying fraction(EF_total),passive emptying fraction(EF_passive),total strain(εs),passive strain(εe)and peak early negative strain rate(SRe)in patient group significantly reduced(all P<0.05).ROC curve showed that the AUC ofεs,εe,and SRe for diagnosis of acute myocarditis was 0.77,0.81 and 0.75,respectively.Conclusion Even with normal left ventricular systolic function,acute myocarditis patients had impaired left atrium storage and conduit function.Quantitative assessment of left atrial strain function based on CMR-FT technology was useful for early diagnosis of acute myocarditis.