Three different aspheric treatment algorithms of laser-assisted sub-epithelial keratectomy in patients with high myopia |
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Authors: | Ji Min Ahn Bong Joon Choi Eung Kweon Kim Bradford Sgrignoli Tae-im Kim |
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Institution: | 1. Siloam Eye Hospital, Seoul, Korea 2. Lee Eye Clinic, 1124-11, Yeonsan-5-dong, Yeonje-gu, Busan, Korea 3. Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Korea 4. Department of Ophthalmology, Cornea Dystrophy Research Institute, Yonsei University College of Medicine, Seoul, Korea 5. Severance Biomedical Science Institute, and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea
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Abstract: | Purpose To compare visual outcomes and quality in high myopia patients treated using one of three aspheric treatment algorithms based on the NIDEK Advanced Vision Excimer Laser System. Methods Sixty eyes of 60 high myopia patients (>?6 diopter) underwent topography-guided (CATz) (20 eyes), wavefront-guided (OPDCAT) (20 eyes), or topography and wavefront-guided (OPA) (20 eyes) laser-assisted sub-epithelial keratectomy. Visual acuity, manifest refraction spherical equivalent (MRSE), ocular and corneal higher order aberrations, corneal asphericity, point spread function (Strehl ratio) and modulation transfer function (MTF) were compared preoperatively and 1, 3 and 6 months postoperatively. Results Six months after surgery, logMAR uncorrected visual acuity was 0.02 ± 0.09 in the CATz group, 0.02 ± 0.07 in the OPDCAT group and 0.02 ± 0.08 in the OPA group, and there were no statistically significant differences (P = 0.5355). No statistical differences were found among the three groups in MRSE (P = 0.3541). Induced spherical aberrations and the change of corneal asphericity were less in the OPA group than in the others (P < 0.0001). The MTF was slightly better in the OPA group than in the others. The Strehl ratio showed no statistically significant differences among the three groups. Conclusions All three aspheric treatment algorithms were safe and effective in correcting high myopia. Among them, the OPA algorithm maintained optical quality and physiologic cornea longer than the others. |
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