呼吸指数判断高原慢性肺源性心脏病急性加重期呼吸衰竭程度及预后的意义

目的探讨高原性慢性肺心病呼吸指数(RI)变化与病情严重程度的关系及判断预后的意义。方法188例高原慢性肺心病急性加重期患者测定了肺泡气氧分压(PAO

Changes of respiratoryindex in chronic pulmonary heart disease at altitudes

Objective:To study the changes and the clinical significance of respiratory index(RI)in chronic pulmonary heart disease(CCP) at high altitude.Methods:Alveolar PO 2(PAO 2) and arterial blood gas were measured in 188 cases of CCP in exacerbation stage and 36 health persons at 2 260-3 300 m altitude.The CCP group was divided upon normal respiratory function(NRF),light respiratory failure(LRF),moderate respiratory failure (MRF) and severe respiratory failure(SRF)subgroup.Results:PaO 2 level was significantly lower in CCP group than that in control group and the levels of A-aDO 2 and RI were higher in CCP group than those in control group.The difference of PaO 2,A-aDO 2 and RI levels between each subgroup and another were significant.The differences of these indexes between in before and after treatment wree significant( P <0.01).The level of RI was significantly negatively correlated with those of PaO 2,PAO 2 and positive correlated with those of PaCO 2 and A-aDO 2.Conclusion:[WT5BZ]The change of RI is significantly correlated with the degree of RF.RI is helpful for evaluating the RF and prognosis in CCP at high altitude.