| 慢性心衰患者尿微量白蛋白、Lp（a）与心功能的关系 |
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| 引用本文： | 谭一菁,李毅夫,赵水平.慢性心衰患者尿微量白蛋白、Lp（a）与心功能的关系[J].心血管康复医学杂志,2001,10(3):219-222. |
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| 作者姓名： | 谭一菁 李毅夫 赵水平 |
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| 作者单位： | 湖南医科大学附属第二医院, |
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| 摘 要： | 目的探讨尿微量白蛋白(MA)、Lp(a)与心功能关系。方法选择60例NYHA心功能Ⅰ～Ⅳ级患者，应用双抗体放免法检测MA，免疫浊度法测定血清脂蛋白(a)［Lipoprotein(a),Lp(a)］水平，并同时应用超声心动图测定射血分数(EF)和左室内径缩短率(FS)。结果MA与年龄、收缩压和血清Lp(a)呈正相关(P均<0.01)lgMA与EF、FS呈负相关(分别为P<0.05，P<0.01)，NYHA心功能与血清Lp(a)和MA呈明显正相关(分别为P<0.05，P<0.01)。结论本组结果提示慢性心衰患者心衰严重程度与MA及Lp(a)水平密切相关。
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| 关 键 词： | 尿微量白蛋白 肌蛋白（a） 心功能 Lp（a） MA 慢性心力衰竭 |
| 文章编号： | 1008-0074(2001)03-0219-04 |
| 修稿时间： | 2001年1月1日 |
Relationship among microalbuminuria and lipoprotein(a) and cardiac function in
patients with chronic cardiac dysfunction |
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| TAN Yi\|jing,LI Yi\|fu,ZHAO Shui\|ping.Relationship among microalbuminuria and lipoprotein(a) and cardiac function in
patients with chronic cardiac dysfunction[J].Chinese Journal of Cardiovascular Rehabilitation Medicine,2001,10(3):219-222. |
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| Authors: | TAN Yi\|jing LI Yi\|fu ZHAO Shui\|ping |
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| Institution: | TAN Yi\|jing,LI Yi\|fu,ZHAO Shui\|pingDepartment of Cardiology,The 2nd Hospital of Hu'nan Medical University,Changsha,Hu'nan,410011 |
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| Abstract: | Objective:To study the relationship among microalbuminuria(MA) and lipoprotein(a)Lp(a)] and cardiac function.Methods:Detected MA by double antibody radioimmunoassay,and detected serum levels of Lp(a) using immunoturbidometry in 60 patients with chronic cardiac dysfunction.Simultaneously measured ejection fraction(EF) and fast shorteness (FS) of left ventricle by echocardiogram.Results:MA was positively related with age,systolic blood pressure and serum Lp(a)( P <0 01 all).There were negative correlation among EF,FS and lgMA( P <0 05, P <0 01 respectively).There was significantly positive correlation among grade of NYHA and serum Lp(a), microalbuminuria( P <0 05, P <0 01 respectively).Conclusion:The results indicated that the severity of cardiac dysfunction in patients with chronic heart failure closely related with microalbuminuria and serum level of Lp(a). |
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| Keywords: | Microalbuminuria Lipoprotein(a) Cardiac function |
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