| 妇消宁泡腾栓最佳处方及质量控制的研究 |
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| 引用本文： | 王淑君,刘卫红,王又红. 妇消宁泡腾栓最佳处方及质量控制的研究[J]. 中国医药导报, 2008, 5(24): 42-43 |
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| 作者姓名： | 王淑君 刘卫红 王又红 |
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| 作者单位： | 1. 郑州大学第一附属医院药剂科,河南郑州,450052
2. 河南中医学院第一附属医院中心实验室,河南郑州,450003 |
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| 摘 要： | 目的：探索妇消宁泡腾栓制备的最佳基质处方及质量控制标准。方法：以pH值为指标采用正交试验法对妇消宁泡腾栓的处方进行优化；薄层色谱法对制剂中的青黛、黄柏进行定性鉴别。结果：优化处方以0.43g酒石酸、0.16g碳酸氢钠、2.00g药物混合为最佳用量比，与基质S40制栓。结论：制剂稳定，质量控制方法简便、准确。
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| 关 键 词： | 妇消宁泡腾栓 正交试验 质量控制 pH 薄层层析法 |
Study on the optimum formula and the quality control for the Fuxiaoning effervescent suppisitiry |
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| WANG Shu-jun,LIU Wei-hong,WANG You-hong. Study on the optimum formula and the quality control for the Fuxiaoning effervescent suppisitiry[J]. China Medical Herald, 2008, 5(24): 42-43 |
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| Authors: | WANG Shu-jun LIU Wei-hong WANG You-hong |
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| Affiliation: | WANG Shu-jun,LIU Wei-hong, WANG You-hong (1.Department of Pharmary, the First Affiliated Hospital of Zhengzhou University ,Zhengzhou 450052 ,China;2.The Central Laboratory, the First Affiliated Hospital of Henan college of TCM ,Zhengzhou 450003 ,China) |
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| Abstract: | Objective：To optimized the formula for the fuxiaoning effervescent suppository and establish its quality control standard. Methods：The formula of the fuxiaoning effervescent suppository was optimized by ortyogonal experiment with pH as index.Indigo Naturalis,Cortex Phellodendri were identified by TLC. Results：The optimized formula was as follows：The used level ratio of tartaric acid,baking soda and medica powder were 0.43,0.16,2.00 g and prepared were S40. Conclusion： The preparation is stationary and the quality control method were convenient and accurate. |
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| Keywords: | pH |
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