放射性核素骨显像诊断乳腺癌骨转移临床应用

目的分析核素骨显像对乳腺癌骨转移的诊断意义。方法对125例乳腺癌患者静脉注射^99Tc^M-MDP 925～1110 MBq行SPECT全身骨显像。结果125例中发现骨转移癌37例，阳性率29．6％。其中无骨痛患者发生骨转移26例；单发转移4例；多发转移33例。发现骨转移病灶的部位以胸廓（126个）、脊柱（81个）为主。乳腺癌术后随回访年限的增加，骨转移阳性率增加。结论核素骨显像可早期诊断乳腺癌骨转移，对于病情估计和制订治疗方案有重要指导意义。

Clinical application of radionuclide bone imaging for detecting bone metastasis of breast carcinoma

Objective To analyze the diagnostic value of radionuclide bone imaging for skeletal metastasis of breast carcinoma.Methods 125 patients with breast carcinoma were injected intravenously 99Tcm-MDP925~1110MBq and examined to observe radiodistribution of whole body.Results In the 125 breast carcinoma patients,37 cases were discovered metastases tumor in bones and the positive rate was 29.6%,in whom 26 were pain-free metastases.Single metastasis were found in 4 cases and multimetastases in 33.Ribs(126) and spinal column(81) were the main metastasis positions.The skeletal metastasis rate was increased along with the prolongation of the follow-up period.Conclusion Radionuclide bone imaging is eligible for finding the skeletal metastasis at early time.Regular follow-up is necessary for securing a right assessment of the illness and for establishing the proper treatment protocols.