Evaluation of patient's Health-Related Quality of Life using a modified and shortened version of the Living With Asthma Questionnaire (ms-LWAQ) and the medical outcomes study, Short-Form 36 (SF-36) |
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Authors: | L. Douglas Ried David P. Nau Timothy J. Grainger-Rousseau |
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Affiliation: | (1) Department of Pharmacy Health Care Administration, College of Pharmacy, University of Florida, Gainesville, FL, Canada;(2) Department of Behavioral and Administrative Pharmacy, School of Pharmacy, West Virginia University, Morgantown, WV, Canada;(3) Faculty of Pharmaceutical Sciences, Division of Pharmacy Practice, University of British Columbia, Vancouver, B.C., Canada |
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Abstract: | Objective: The specific objectives of this study were to: 1) study the effect of moderate-to-severe asthma on patient's Health-Related Quality of Life (HRQoL) as measured by the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36) and 2) evaluate the construct validity of a modified and shortened version of the Living With Asthma Questionnaire (ms-LWAQ) using the SF-36 as a concomitant measure of HRQoL. Methods: Cross-sectional, telephone or mail surveys of asthmatic patients enrolled in two central Florida managed care organizations. Results: All subscales of the SF-36 and four subscales of the ms-LWAQ demonstrated adequate reliability in this population (Cronbach >0.72). The subscales of the SF-36 most affected by patient's asthma were: general health perceptions, vitality and physical role functioning. These three subscales were correlated with four subscales of the ms-LWAQ: consequences, seriousness, affect and leisure. Six of the eight SF-36 subscales and all of the ms-LWAQ subscales were associated with patient's emergency department and hospital utilization. Conclusion: The ms-LWAQ and SF-36 are valid as useful measures of asthma patient's HRQoL in this cross-sectional study. Severity of disease, as measured by health care utilization, was significantly associated with HRQoL. |
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Keywords: | Asthma Health-Related Quality of Life Living with Asthma Questionnaire SF-36 Utilization |
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