胆结石成因与地球化学环境关系的探索

贵州省贵阳市以胆固醇结石为主的胆囊结石占77.56％,而从江县以胆色素结石为主的原发性肝胆管结石占66.89％。作者取贵阳市和从江县两地区胆石进行成份分析、水质分析、土壤微量元素分析,并比较两地区地理、地貌、地层、岩性、气候和生活习性差异,以探索胆结石成因与地球化学环境的关系。初步发现胆固醇结石多发于碱性硬水地区,而胆色素结石多发于酸性软水地区。

The Relationship Between the Regional Environment and the Genesis of Gallstones

The relationship between regional environment and gallstone genesis of Guiyang City and Chongjiang County has been studied.The geologic, geographic and climatic situation between those of two places are different :Guiyang City is located in the alpine basin of middle Guizhou covered by limestone with a temperate climate, on the contrary, Chongjiang County in the south-east of Yunnan-Guizhou plateau covered by slate with a subtrop- ical mild-humid climate.The differences are also shown in gallstone types, there are 77.56% cholesterol stones in Guiyang, while 68.89% pigmental stones in Chongjiang.The contents of K, Na, Ca, Mg, Mn, Cl, Fe, Cu, Co, Al and P stones in Chongjiang are higher than those in Guiyang.As a drinking water acidic soft water, pH=6.03, rich in Na~+, K~+ and Cl~-for the Chongjiang and alkali hard water pH=7.9, rich in Ca~(2+), Mg~(2+), dissolved gas O_2, HCO_3~-, SO_4~(2-) and plasma NH_4NO_2~-, NO_3~-is typical for the Guiyang, The contents of Pb, Ni and Cr of soil the Guiyang are 21, 18, 84 times greater tnan tnose in the Chongjiang respectively.From above described, a preliminary conclusion can be gotten, that cholesterol gallstone mostly formed in alkali hard water area, and pigmental gallstone in acidic soft water area.