原发性小肠肿瘤47例临床分析

目的：探讨原发性小肠肿瘤的临床表现、诊断方法及预后。方法回顾性分析47例原发性小肠肿瘤患者的临床资料。结果47例原发性小肠肿瘤临床表现无特异性，术前确诊率为34．0％（16／47）。良性肿瘤占12．8％（6／47），病理以腺瘤为主，预后好。恶性肿瘤占70．2％（33／47），贫血是其较为突出的临床表现，病理主要为腺癌（29例，失访3例），好发于十二指肠，预后差。26例腺癌患者1、2、3、5年生存率分别为67．4％、42．4％、29．4％、22．8％，中位生存期为20．3个月。间质瘤占17％（8／47），主要来源于空肠，以腹部包块为主要表现，术后使用靶向药物有助于改善患者预后。结论小肠肿瘤发病率低，但以恶性为主，预后差，采取有效的检查手段尽早发现病灶并行手术切除是治疗的关键。

Clinical analysis on 47 cases of primary small intestine tumor

Objective To investigate the clinical characteristics ,diagnosis and prognosis of primary small intestine tumor . Methods Retrospective analysis was performed on the clinical data collected from the 47 cases of primary small intestine tumor . Results The clinical characteristics were non‐remarkable ,the preoperative diagnosis rate was 34 .0% (16/47) .Six cases (12 .8% ) were benign tumor ,adenoma was the main pathological type and the prognosis was good .Thirty‐three cases (70 .2% ) were malig‐nant tumor ,manifested mainly as anemia ,adenocarcinoma was the main pathological type ,originated from the duodenum mostly and the prognosis was poor .The 1 ,2 ,3 and 5 year survival rates of 26 cases in small intestine adenocarcinoma were 67 .4% ,42 .4% , 29 .4% and 22 .8% ,respectively ,and the median survival time was 20 .3 months .Eight cases(17 .0% ) were gastrointestinal stromal tumor ,most originated from the jejunum ,abdominal mass was the mainly clinical feature ,targeted drugs could help to improving the prognosis .Conclusion The incidence of primary small intestine tumor is low ,but most of them are malignant and the prognosis is poor .Find lesion in early stage with effective examinations and undergoing surgical resection are the key of treatment .