| Experimental research of curing sciatic nerve injury using nerve growth factor and basic fibroblast growth factor combination |
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| 作者姓名： | 梁崇礼 赵稳兴 |
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| 作者单位： | DepartmentofMedicalExperiment,KunmingGeneralHospitalofChengduMilitaryofPLA,Kuming650032,YunnanProvince,China |
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| 摘 要： | AIM:To explore the co-effect of nerve growth factor (NGF)and basic fibroblast growth factor(bFGF) on the sciatic nerve after injury.METHODS:96 rats were divided into normal saline group,NGF group,bFGF group and NGF bFGF group.Sciatic nerve function index(SFI),nerve conduction velocity,regeneration axon counting were detected in the 3rd,6th,9th,12th week postinjury.RESULTS:The end of SFI,nerve conduction velocity,regeneration axon counting in NGF bFGF group were higher than those in the other groups.CONCLUSION:The co-effect of NGF and bFGF on sciatic nerve is better than the effect of NGF or bFGF alone.
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| 关 键 词： | 神经生长因子 碱性成纤维细胞生长因子 联用 治疗 坐骨神经损伤 实验研究 |
Experimental research of curing sciatic nerve injury using nerve growth factor and basic fibroblast growth factor combination |
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| Institution: | DepartmentofMedicalExperiment,KunmingGeneralHospitalofChengduMilitaryofPLA,Kuming650032,YunnanProvince,China |
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| Abstract: | AIM:To explore the co-effect of nerve growth factor (NGF)and basic fibroblast growth factor(bFGF) on the sciatic nerve after injury.METHODS:96 rats were divided into normal saline group,NGF group,bFGF group and NGF+bFGF group.Sciatic nerve function index(SFI),nerve conduction velocity,regeneration axon counting were detected in the 3rd,6th,9th,12th week postinjury.RESULTS:The end of SFI,nerve conduction velocity,regeneration axon counting in NGF+bFGF group were higher than those in the other groups.CONCLUSION:The co-effect of NGF and bFGF on sciatic nerve is better than the effect of NGF or bFGF alone. |
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