| 新疆克拉玛依地区几株利什曼原虫分离物的同源性分析 |
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| 引用本文： | 汪俊云,瞿靖琦,管立人,任灏远. 新疆克拉玛依地区几株利什曼原虫分离物的同源性分析[J]. 中国寄生虫学与寄生虫病杂志, 1996, 0(4) |
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| 作者姓名： | 汪俊云 瞿靖琦 管立人 任灏远 |
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| 作者单位： | 中国预防医学科学院寄生虫病研究所，美国芝加哥医学院微生物免疫学系，新疆石油局总医院皮肤科 |
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| 摘 要： | 目的：确定新疆克拉玛依皮肤利什曼病患者和硕大白蛉吴氏亚种体内利什曼原虫的种。方法：通过酶切电泳及ＤＮＡ杂交的方法对当地病人体内和蛉体内的利什曼原虫以及参考虫株的ｎＤＮＡ及ｋＤＮＡ的同源性分析，研究克拉玛依病人和蛉体内利什曼原虫的基因型。结果：经ｎＤＮＡ基因型分析，表明病人与蛉体内原虫与婴儿利什曼原虫同源性大。结论：当地皮肤利什曼病的病原体为婴儿利什曼原虫，硕大白蛉吴氏亚种为该病的媒介。
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| 关 键 词： | 皮肤利什曼病 婴儿利什曼原虫 DNA杂交 |
ANALYSIS ON HOMOLOGY IN SEVERAL ISOLATES OF LEISHMANIA FROM |
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| Abstract: | AIM: To identify Leishmania isolates in Phlebotomus (P.major wui) and cutaneous leishmaniasis (CL) patients from,Karamay, Xinjiang . METHOD:Study on the characterization and genotype of Leishmania isolates from the sandflies, CL patients and the reference strain by analysing simultaneouly kinetoplast and chromosonal DNA. RESULTS: The nDNA genotype analysis showed that isolates from the sandflies, CL patients and Leishmania infantum are highly homologous. CONCLUSION: Leishmania infantum is the pathogen of cutaneous leishmaniasis in Karamay, Xinjiang, and P.major wui, the vector of this disease. |
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| Keywords: | Cutaneous leishmaniasis Leishmania infantum DNA hybridization |
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