Dynamic imaging of contrast enhancement in brain tumors |
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| Authors: | P R Bullock P Mansfield P Gowland B S Worthington J L Firth |
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| Affiliation: | Department of Physics, University of Nottingham, United Kingdom. |
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| Abstract: | Gadolinium-DTPA has been shown to be a good probe for demonstrating defects in the blood-brain barrier, but it has a rapid rate of elimination so that peak circulating levels are short-lived. In this study ultrafast echo-planar imaging has been used in combination with a bolus injection of gadolinium-DTPA to evaluate perfusion within brain tumors and to assess the degree of disruption of the blood-brain barrier. The temporal profile of enhancement may allow discrimination between different tumor types. |
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