| C—erbB—2、nm23蛋白在口腔粘膜鳞癌组织中的表达 |
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| 引用本文： | 葛明华,张谷,王可敬. C—erbB—2、nm23蛋白在口腔粘膜鳞癌组织中的表达[J]. 肿瘤学杂志, 2001, 7(4): 218-219 |
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| 作者姓名： | 葛明华 张谷 王可敬 |
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| 作者单位： | 浙江省肿瘤医院, |
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| 摘 要： | [目的]研究口腔粘膜鳞癌组织中C-erbB-2蛋白和nm23蛋白的表达及意义。[方法]采用免疫组化方法检测80例口腔粘膜鳞癌组织中C-erbB-2蛋白和nm23蛋白的表达。[结果]口腔粘膜鳞癌组织中C-erbB-2蛋白的阳性表达率为67.5%，nm23蛋白的阳C-erbB-2蛋白和nm23蛋白的表达状况可能提示口腔粘膜鳞癌患者的预后。
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| 关 键 词： | 口腔肿瘤 鳞状细胞癌 C－erbB－2蛋白 nm23蛋白 预后 |
| 文章编号： | 1671－ 170X（ 2001） 04－ 0218－ 02 |
| 修稿时间： | 2001-04-27 |
2 and nm23 Protein in Oral Squamous Cell Carcinoma |
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| GE Ming hua,ZHANG Gu,WANG Ke jing. 2 and nm23 Protein in Oral Squamous Cell Carcinoma[J]. Journal of Chinese Oncology, 2001, 7(4): 218-219 |
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| Authors: | GE Ming hua ZHANG Gu WANG Ke jing |
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| Abstract: | To investigate the expressions of C erbB 2 and nm23 protein in oral squamous cell carcinoma. Immunohistochemical method was used to measure the expressions of C erbB 2 and nm23 protein in 80 cases of oral squamous cell carcinoma. The positive rates of C erbB 2 and nm23 protein were 67.5%and 38.8% respectively. The C erbB 2 protein expression was associated with histologic grade and clinical stages, but nm23 protein expression was only correlated with lymph node metastasis. [Conclusion] C erbB 2 and nm23 protein expressions in oral squamous cell carcinomas could predict tumor prognosis. |
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| Keywords: | oral neoplasms carcinoma squamous cell protein C-erbB-2 protein nm23 prognosis |
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