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OBSERVATIONS ON MITOSIS IN PSORIATIC EPIDERMIS |
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| Authors: | LIONEL FRY R. M. H. McMINN |
| Affiliation: | Dermatology Department, St. Mary's, London, W.2 (Dr Fry), and the Anatomy Department, King's College, London, W.C.2 (Professor McMinn) |
| Abstract: | SUMMARY.— Mitotic counts in psoriatic epidermis removed from (a) the centre and edge of a single plaque in 17 patients, and (b) lesions at 3 different sites—the arm, leg and back—in 16 patients, have been compared. Mitotic counts at the centre and edge of a plaque were similar for an individual patient, although there was variation in the group as a whole. There was no significant difference between the average centre and edge counts. The counts from the arm, leg and back were similar for an individual patient despite variation between patients. There was no evidence of any consistent variation between the 3 sites. These results suggest that the factors influencing mitosis in psoriasis at any given time are similar for all lesions and each part of a lesion in an individual patient, although there are variations between patients. |
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