甲亢伴周期性麻痹发作的临床特点与代谢特征

目的　探讨甲亢伴周期性麻痹的临床与代谢特点。方法　分析 38例甲亢并周期性麻痹发作的临床特征 ,同时检测患者的血钾、血糖、血磷、血镁、醛固酮及胰岛素水平。结果　本病多发于青壮年男性 ,部分患者甲亢的临床症状与体征基本缺如 ,瘫痪下肢比上肢重 ,多有瘫痪肢体肌肉胀痛感 ,瘫痪肢体腱反射亢进或正常 ,出现低钾血症、低磷酸盐血症、低镁血症、血浆醛固酮升高、血糖及胰岛素水平升高。结论　周期性麻痹继发于甲亢的高比例应引起重视 ,治疗的关键在于补钾和甲亢的控制

The Clinical and Metabolizing Features of Graves Disease Accompanied by Periodic Paralysis

Objective To explore the clinical and metabolizing features of Graves disease accompanied by periodic paralysis. Methods Clinical features of 38 patients with Graves disease accompanied by periodic paralysis were analysed and levels of plasma potassium, sugar, magnesium, phosphor, aldosterone and insulin were tested simultaneously.Results The disease was often seen in male youth and prime of life;some patients' paralyses of lower limbs was severer than those of upper limbs;the senses of swelling and pain were frequently felt by the muscles of paralyzed limbs; tendon reflex of paralysed limbs often became enhanced or normal;hypopotassemia,hypomagnesemia,hypophosphatemia,hyperglycemia,hyperaldosteronism and hyperinsulinemia occurred easily.Conclusion Grave disease accompanied by periodic paralysis should be paid much attention to and it was very important to control the symptoms of Graves diseases and supplement potassium.