20例新生儿肺动脉高压的临床分析

新生儿动脉高压症２０例，均由超声心动图证实。其中原发性肺动脉高压３例；继发性肺动脉高压１７例，１２例继发于先天性心脏病，５例继发于围产期窒息、吸入性肺炎及湿肺。４例先天性心脏病的患儿用硫酸镁治疗，临床有效。治疗后动脉血氧饱和度和动脉化毛细血管法测定氧分压明显升高，二氧化碳分压降低，吸入氧浓度减少，没有发现明显的药物副作用。本组死亡６例，１４例存活者中２例自愈率，１例手术治愈，６例药物治愈，２例仍存

Clinical analysis for twenty neonates with persistent pulmonary hypertension

Persistent pulmonary hypertension (PPH) were diagnosed by ultrasono cardiography in 20 newborn infants in whom there were three primary and 17 secondary PPH. PPH was caused in 12 cases by congenital heart disease and in 5 cases by perinatal asphyxia, aspiration pneumonia and wet lung, respectively. Four PPH cases with congenital heart disease received magnesium sulphate (MgSO4) effectively. The arterial blood oxygen saturation (SaO2) and arterial partial pressure (PaO2) determined by capillary method increased and partial pressure of carbon dioxide (PaCO2) decreased significantly after treatment. The amounts of supplemental oxygen (FiO2) were also found to reduce obviously. No any side effects were found on MgSO4. 6 neonates were earlily dead, amony whom the recovery with medical management was got in 6 cases,the recovery via operation in 2 cases, spontaneous recovery in 2 cases, the existence of PPH in cases and missing follow-up in 3 cases.