Pseudotypes of vesicular stomatitis virus determined by exogenous and endogenous avian RNA tumor viruses |
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Authors: | D N Love R A Weiss |
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Affiliation: | Imperial Cancer Research Fund Laboratories, P.O. Box 123, 44, Lincoln''s Inn Fields, London, WC2A 3PX, England |
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Abstract: | Vesicular stomatitis virus (VSV) forms pseudotypes with envelope components of avian RNA tumor viruses. The VSV pseudotypes possess the specific host range, interference, and antigenic properties of the tumor virus. Growth of VSV in cells expressing chick cell-associated helper factor coded by an endogenous viral genome yields pseudotypes with the envelope specificity of the helper factor. |
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